P07.10: Screening performance for trisomy 21 comparing first trimester combined screening and a first trimester contingent screening protocol including ductus venosus and tricuspid flow
نویسندگان
چکیده
منابع مشابه
Second-trimester genetic sonography after first-trimester combined screening for trisomy 21.
OBJECTIVE The purpose of this study was to evaluate the trisomy 21 screening performance of the first-trimester combined test followed by second-trimester genetic sonography. METHODS This retrospective cohort study included all women with singleton pregnancies undergoing combined screening followed by genetic sonography at 17 to 21 weeks from January 1, 2005, to January 31, 2008. Combined tes...
متن کاملProspective first-trimester screening for trisomy 21 in 30,564 pregnancies.
OBJECTIVE This study was undertaken to evaluate the performance of a 1-stop clinic for first-trimester assessment of risk (OSCAR) for trisomy 21 by a combination of maternal age, fetal nuchal translucency (NT) thickness, and maternal serum-free ss- human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein-A (PAPP-A). STUDY DESIGN OSCAR was carried out in 30,564 pregnancies a...
متن کاملFirst-trimester screening for trisomy 21 using alpha-fetoprotein.
OBJECTIVE To investigate the potential value of adding maternal serum alpha-fetoprotein (AFP) to free β-human chorionic gonadotropin (β-hCG) and PAPP-A and fetal nuchal translucency (NT) thickness in first-trimester screening for trisomy 21. METHODS In this case control study, serum AFP was measured in 100 trisomy 21 and 1,500 euploid pregnancies in which screening for trisomy 21 had been per...
متن کاملFirst-trimester contingent screening for trisomy 21 by biomarkers and maternal blood cell-free DNA testing.
OBJECTIVE To define risk cut-offs with corresponding detection rates (DR) and false-positive rates (FPR) in screening for trisomy 21 using maternal age and combinations of first-trimester biomarkers in order to determine which women should undergo contingent maternal blood cell-free (cf) DNA testing. METHODS From singleton pregnancies undergoing screening for aneuploidies at three UK hospital...
متن کاملFactors predicting a positive pregnancy screening test at first trimester
Background: For every pregnant woman, it is possible to have a child with chromosomal abnormalities. Although this possibility is not very high, by performing screening tests and considering the mother's background factors, we can largely realize the real extent of this possibility. Many comorbidities (like high blood pressure, diabetes, and obesity) and high-risk exposures (like alcohol consu...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics & Gynecology
سال: 2012
ISSN: 0960-7692
DOI: 10.1002/uog.11848